SubtiBank SubtiBank
yfkC [2018-07-31 10:46:40]
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yfkC [2018-07-31 10:46:40]

mechanosensitive channel, similar to MscS
locus
BSU07940
pI
5.29
mw
32.05 kDa
protein length
280 aa Sequence Blast
gene length
840 bp Sequence Blast
function
resistance to osmotic downshock
product
mechanosensitive channel, similar to MscS
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.7|Coping with hypo-osmotic stress]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    867,164 → 868,006

    The protein

    Structure

  • [PDB|3UDC] (36% identity)

    • [SW|Localization]

  • cell membrane [Pubmed|19252899]

    • Expression and Regulation

    Operons

    genes
    [gene|62718BBECEB18244B5CC877509679F5F9A0C50CD|yfkA]-[gene|5ACE71EBBDCEB0C534A91DE303FD8069BEFDD6A1|yfkC]
    description
    [Pubmed|22383849]
    view in new tab

    Biological materials

    Mutant

  • MGNA-C271 (yfkC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2269 NBRP B. subtilis, Japan]
  • 1A959 ( ''yfkC''::''tet''), [Pubmed|18310427], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A959&Search=1A959 BGSC]
  • BKE07940 (Δ[gene|5ACE71EBBDCEB0C534A91DE303FD8069BEFDD6A1|yfkC]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE07940 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CGTAAGTGTTTCTTTCATCC, downstream forward: _UP4_TAAACAAAAAAACTGATTCC
  • BKK07940 (Δ[gene|5ACE71EBBDCEB0C534A91DE303FD8069BEFDD6A1|yfkC]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK07940 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CGTAAGTGTTTCTTTCATCC, downstream forward: _UP4_TAAACAAAAAAACTGATTCC

    • Labs working on this gene/protein

  • [SW|Erhard Bremer], University of Marburg, Germany [http://www.uni-marburg.de/fb17/fachgebiete/mikrobio/molmibi homepage]

    • References

    Reviews

  • 12626684,22685280

    • Original Publications

  • 17665170,18310427,19252899,22383849